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This work was supported by the National Institute of Diabetes, Digestive and Kidney Diseases R00DK1208689 and P30DK045735 grants, the National Institute of Health Yale-Murine Tissue Mapping Center Grant U54 AG079759 and the National Institute of Health National Institutes of Aging Grant P30AG066508

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These results suggest that the uptake of GLP-1RAs into the brain via tanycytes is important for their anti-obesity effects

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