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Additionally, the applicant asserted that CMS previously made distinct device categories for anatomical locations when it created device category codes C1888 (Catheter, ablation, non-cardiac, endovascular (implantable)), effective July 1, 2002, and C1886 (Catheter, extravascular tissue ablation, any modality (insertable)), effective January 1, 2012

Al-Otaish et al., 2018

In the very early stages, microglial nodules are seen without lymphocytic infiltration (Singh et al., 2013) suggesting that these innate immune cells were reacting to a subtle early pathology that predated the arrival of T or B cells

Wink S, Hiemstra SW, Huppelschoten S, Klip JE, van de Water B