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This requires urgent evaluation regardless of whether the cause is semaglutide, gallstones, or another trigger

Approval will likely require prior authorization and step therapy

Across the four clinical trials, mean baseline ages ranged between 55.1 and 57.8 with between 6.6 and 8.6 years of historical diabetes diagnoses, and baseline HbA1c levels ranging between 8.1 and 8.3

However, because glucagon-like peptide-1 receptor agonists work to slow gastric emptying, a safety concern has been raised in patients undergoing deep sedation or general anesthesia regarding gastric aspiration, and considering their long half-life in the blood, they are difficult to manage in the perioperative period