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But maintaining weight loss after transitioning off GLP-1s requires improving the systems that regulate hunger, energy, muscle mass, blood sugar, recovery, hormones, inflammation, and metabolic flexibility

The most common side effects (incidence 5%) include nausea, diarrhea, vomiting, constipation, stomach-area pain, heartburn, injection-site reactions, sleepiness, allergic reactions, burping, hair loss and acid reflux disease

Journal of Applied Phycology 5:50313

Semaglutide alone accounted for 64% of all GLP-1 receptor agonist poison control contacts during the study period far outpacing other drugs in the class