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They found that even without causing weight loss, retatrutide had anti-tumor effects that were similar to the currently used (and incredibly expensive) immunotherapy.[ref] A 5-year mortality study in colon cancer patients showed that GLP-1 RA use decreased mortality risk by 60% in obese patients.[ref] Animal studies may show the mechanism

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Dual-compound options like GLP-Squared Injection ($289/mo) balance receptor activation differently, potentially reducing cold sensitivity for some patients while maintaining weight-loss efficacy