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Glyoxalase system in clinical diabetes mellitus and correlation with diabetic complications

The oxidative stress (low glutathione) associated with chronic disease may actually disable the thermostat called Nrf2 that turns on enzymes that make glutathione

It is interesting to note that nutrients, particularly polyphenols, vitamins, probiotics, and PUFAs, follow the concept of hormesis, a biphasic dose-response process by which small, nontoxic stresses or mild stress are used to induce cellular adaptive responses that protect the biological system against subsequently large and potentially lethal stresses of the same, similar, or different nature

Impact of acute hyperglycemia on myocardial infarct size, area at risk and salvage in patients with ST elevation myocardial infarction and the association with exenatide treatment results from a randomized study