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Statistical details, including the test used and exact p values, are provided in the figure or figure legends

Gastrointestinal symptoms that some patients experience while on GLP-1 therapysuch as nausea, reduced appetite, or altered bowel habitsgenerally resolve as the medication clears from the system, typically within 1-2 weeks for short-acting formulations and within 4-8 weeks for long-acting preparations, corresponding to their elimination timelines

Specifically, rapamycin binds to FKBP12, forming a complex that inhibits mTORC1 activity

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