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Preclinical studies suggests BPC 157 has the following effects: Reduced inflammation of the gut and enhanced repair of the intestinal lining
The FDA warns that both CJC-1295 and ipamorelin carry risks of immunogenicity (triggering immune responses) and cardiovascular effects, including "increased heart rate and systemic vasodilatory reaction." One clinical trial of CJC-1295 was discontinued following a participants death, though the attending physician believed the event was "unrelated to treatment." Neither CJC-1295 nor ipamorelin is FDA-approved
In addition, Pycnogenol s antioxidant effects were shown by a significant decrease of 15-F 2t -Isoprostane, a marker of lipid peroxidation from 0.71 0.09 pg/ml to 0.66 0.13 pg/ml, with no change in the placebo group
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