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d , Counterflow transport of [ 3 H]GSSG into WT or 2YA-mutant SLC33A1 reconstituted liposomes preloaded with 10 mM unlabelled GSSG, followed by incubation with 20 M [ 3 H]GSSG for 40 min

Pituitary and hypothalamic signaling: Experiments evaluating downstream intracellular pathways in pituitary somatotrophs and hypothalamic circuits in response to combined ghrelin receptor and GHRH receptor stimulation

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Subsequent studies revealed heightened sensitivity of MM cell lines to ferroptosis, with combined bortezomib and iron chelation exhibiting superior efficacy in suppressing disease progression compared to monotherapy, these findings collectively underscore the critical role of ferroptosis in MM pathogenesis (Figure 3)