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Biosimilars and similar biologics (for injectable GLP-1 analogues such as liraglutide, dulaglutide, and semaglutide) if companies can demonstrate comparability in structure, function, and clinical performance.[11] This framework is what enabled Indias earlier waves of affordable insulin, cancer drugs, and biologics and it is now being replicated for GLP-1 therapies

This effect of GLP-1s on inflamation is part of why the heart protection appeared larger than weight loss alone could explain

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15-17 The first case report documenting the successful use of semaglutide in treating HS by Drumm et al 18 also showed a reduction in weight (24 kg), DLQI, narcotic analgesia use (from daily to not daily), and Hurley stage after six months of treatment