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Insufficient NAD + synthesis leads to reduced mitochondrial respiration and phagocytosis, contributing to heightened inflammatory responses
Convenient tests that measure total plasma antioxidant activity by a commercial kit, or so-called TRAP and FRAP assays that have been used in clinical trials (10, 80), are misleading in monitoring micronutrient therapy because they are largely influenced by those compounds : ascorbic acid contributes 20% to the FRAP reading, vitamin E 5%, -carotene very little and thiols none (30)
Vallf D, Maccioni P, Colombo G, Mandrapa M, Jrnulf JW, Egecioglu E, et al
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