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Cleveland Clinic explains that cutting calories too aggressively can lead to side effects like fatigue, headaches, dehydration, nausea and irritability, and that overly restrictive diets can also slow your metabolism. While losing weight on a calorie deficit, staying hydrated, and eating enough protein-rich foods can help you feel fuller and stay active. Do I need heavy weights to protect muscle on GLP-1 Not necessarily

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GLP-1 medications are associated with dose-dependent side effects, particularly gastrointestinal symptoms

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