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References: Hu W, Song R, Cheng R, Liu C, Guo R, Tang W, Zhang J, Zhao Q, Li X, Liu J

Elevated blood sugar directly damages the endothelial lining through a process called glycation, where sugar molecules bind to proteins and lipids, forming advanced glycation end-products (AGEs)

Taken together, if the five isozymes were sorted according to their ability in mitigating the abnormal increase in LDH, ROS, DNA damage, as well as their facilitation effects on the production of AFBO-GSH, the GSTA2X had superior performance compared to GSTA3, GSTT1L, GSTZ1-1 and GSTZ1-2