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Additionally, a thorough exploration of immune function and oxidative stress level of kidney-yang deficiency syndrome is warranted to unravel potential pathogenic pathways leading to diarrhea associated with kidney-yang deficiency syndrome

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If NF- B-specific activators can be used simultaneously with histidine treatment and it is demonstrated that this operation can completely or partially block the anti-inflammatory effect of histidine, it will provide the most direct causal evidence for the mechanism