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Statements Author contributions LC, DX, and JZ: design of the study and writing of the manuscript

Hardeland R (2016) Melatonin and synthetic melatoninergic agonists in psychiatric and age-associated disorders: successful and unsuccessful approaches

Nevertheless, as the simultaneous activation of GLP-1 and GIP receptors in preclinical models results in greater WL and glucose-lowering efficacy compared to activation of each receptor alone [38,39,40], the interest for the development of unimolecular GLP-1 and GIP RA was increased, despite that this additive effect in food intake and glycaemia was not observed in some acute clinical studies [41, 42]

That may include: better overall energy and productivity more consistent fat loss progress fewer start and stop cycles improved mood and motivation At this stage, many people continue injections as part of their wellness routine, especially if they notice they feel more like themselves when they stay consistent