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Praga, M

Key Takeaways Doctors recommend stopping GLP-1 medications a couple of months before trying to get pregnant

The cerebrovasculature is a very bioenergetically active tissue with capillary endothelial cells having been shown to possess five times more mitochondria than muscle cells (Oldendorf and Brown, 1975) and transport 10 times their weight in glucose each minute across the BBB, along with accomplishing other energetically costly cellular processes (Cunnane et al., 2011)

Furthermore, cell-specific transneuronal tracing indicated labeling from the vagal sensory ganglion to dopamine cells in the substantia nigra, but not to brain regions directly regulating locomotion 86