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Developed through systematic structure-activity relationship studies, it was engineered to optimize GH-releasing potency while minimizing effects on cortisol and prolactin secretion, a selectivity profile that distinguishes it from earlier, less refined GHRPs such as GHRP-2 and GHRP-6

This disrupts multiple neurotransmitter systems, including dopamine, GABA, glutamate, and serotonin, further exacerbating neurotransmission dysfunction