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GLP-1 receptor agonists like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) begin affecting appetite and blood sugar within days to weeks, but clinically meaningful outcomes develop more gradually

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My love for food is gone and its kind of depressing I could see myself falling into a depression if I stayed on this long term. Jaclyn even shared that the medication made eating unenjoyable at times, saying she went to an amazing sushi restaurant but felt like I could throw up until the next morning. Now, after three months, Jaclyn says shes hit her goal weight and is choosing to stop the injections so as not to get too carried away

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