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About the prescription of exenatide and liraglutide, both compounds are contraindicated in MTC patients or multiple endocrine neoplasia syndrome 2 (MEN 2) patients due to the increased incidence of C-cell hyperplasia and tumors combined with elevated calcitonin levels in preclinical studies in rodents

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Further complicating the impact of this disease, mild and moderate hypertension are usually asymptomatic, and their presence (and the subsequent increase in cardiovascular risk) is often unrecognized

Singh S, Loke YK, Furberg CD