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Free Rad Biol Med

Additionally, the downregulation of vimentin, a marker for epithelial-to-mesenchymal transition, is linked to changes in transforming growth factor (TGF)- signaling, affecting cell differentiation and impairing regenerative processes in the bladder

The autophagy modulation and cell death observed in our study might reflect two separate events occurring concurrently with both being triggered by lysosomal accumulation

Following reports of bacterial endotoxin in the pelvic cavity and menstrual blood 37 , and sub-clinical uterine infections found in patients with endometriosis 56 , Khan et al., 2017 proposed that microbes might activate inflammatory cascades by binding Toll-like receptors, and contribute to endometriotic lesion establishment, growth and progression