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Antioxidants 12 (2), 281

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Proteins analysis in synovial membrane Researchers have identified proteins that are differentially expressed in synovial membrane, linking menopause with the progression of OA and potentially leading to novel diagnostic and therapeutic strategies [65].Elevated levels of vitronectin fragments (amino acids 381397) have been identified in the serum of OA patients, which can interact with V6 on human fibroblast-like synoviocytes to inhibit the activation of TGF-1, potentially promoting fibrosis in OA [66]