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Malate is cheaper Citrulline malate costs a fair bit less to formulate, which is often why supplement companies push the use of it to keep costs down

Research observations include: Alterations in appetite signaling pathways Changes in libido-related responses Mild fluctuations in energy levels Temporary cardiovascular responses such as increased heart rate These effects are associated with activation of MC3R and MC4R receptors, which play roles in metabolic and neuroendocrine regulation

Treatment regimens and guidance: The British National Formulary (BNF) and NICE Clinical Knowledge Summaries outline treatment regimens for B12 deficiency

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