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Early intervention is generally associated with better outcomes, and clinicians should not attribute new joint symptoms solely to pre-existing conditions without appropriate reassessment

Less common side effects include mild headaches or dizziness

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Exposure to the novel environment increased the densities in both control and DG-NR1KO mice ( p = 1.7 10 4 and 0.008, respectively, df = 31, Tukeys HSD test) while the densities were lower in DG-NR1KO mice than controls regardless of whether they were exposed to novel environment or not ( p = 1.7 10 4 and 2.0 10 4 , respectively, df = 31, Tukeys HSD test)