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For example, NOX1-derived ROS in epithelial cells have been shown to promote wound healing responsesROS can act as second messengers to activate proliferative signaling and cytoprotective genes in epithelial cells (126, 127)

The increased apoptosis observed was presumably initiated by the altered mitochondrial membrane potential causing release of cytochrome c and activation of the intrinsic apoptotic pathway

(1) Peptides play an important role in many internal processes and biological functions , including hormone regulation, cell signaling, immune response, and more

AC treatment could also inhibit p38, TNF, PI3K/AKT, and NFB signaling pathways in the LPS-induced RAW264.7 cells (Muhtar et al