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in free solution, followed by blood sampling at regular intervals from the saphenous vein up to 6 hours after administration, to measure blood glucose levels

Mean (SD) PROMIS PF T-scores were 40.3 (6.6) for -TDT and 43.0 (7.5) for -TDT compared with published US norm of 59.7 (8.0).Mean (SD) WPAI-Thalassemia overall work impairment scores were 58.8% (20.8%) for -TDT and 41.3% (26.8%) for -TDT, and activity impairment scores were 56.7% (26.7%) and 41.2% (26.2%), respectively

B12 is an essential vitamin with many functions in the body

Isotopic Labelling: Internal standards containing C-labeled GSH and GSSG were prepared in antioxidant buffer to ensure quantitation accuracy