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When a toxic dose of paracetamol is ingested, the normal glucuronide pathway is saturated and large amounts of NAPQI are produced

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Glutathione is involved in detoxification, it binds to toxins, such as heavy metals, solvents, and pesticides, and transforms them into a form that can be excreted in urine or bile

Furthermore, it has been reported that lysosomes, peroxisomes, Golgi apparatus, endoplasmic reticulum (ER), and ribosomes are also cleared from the erythroid lineage cells in an autophagy-dependent fashion [32, 36]