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454,455 In this approach, oligonucleotides or their analogs are covalently linked to one or more peptide residues to form POCs

PMID: 5 FabbriniESullivanSKleinS

By employing 3D hydrogels typically characterized by small, micron-sized pores, the Kamm and Swartz labs have shown that (patho)physiologically relevant flow velocities can trigger migration of MDA-MB-231 in the upstream (against the flow) and downstream (with the flow) direction [231, 232]