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However, its precursor TMA has a negative effect on bloodbrain barrier function [247]

doi: 10.1016/s0304-3940(02)00667-5

The vast majority of evidence comes from MCT or hypoxia animal models, whose pathological characteristics differ from human PH, lacking in-depth verification in models that are more similar to human disease states

Rhonda Patrick: So, vitamin D and SNPs that basically make the conversion of vitamin, either vitamin D precursor into D3, or in D3 into 25 hydroxyvitamin D or into the active steroid hormone, which is 125 hydroxyvitamin D