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On histology, basal keratinocytes showed melanin pigment and lamina propria contained melanophages and congested blood vessels [Figures 3a and 3b]
A subgroup of the patients had functional MRI (fMRI) and singlephoton emission CT (SPECT) scans performed at baseline and after 26 weeks of treatment, to investigate potential neurobiological changes (the clinical study has been completed, and the manuscript is in preparation, ClinicalTrials.gov identifier NCT03232112) (Antonsen et al., 2018)
10.1242/dev.01921 Development 46 TianA.BenchabaneH.WangZ.AhmedY
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