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Following subcutaneous administration, tirzepatide reaches peak plasma concentrations (Tmax) in 8 to 72 hours, with steady-state concentrations achieved after approximately 4 weeks of once-weekly dosing

Change pillow covers and bedsheets to fresh ones at regular intervals, to prevent bacteria

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This direct transport of extracellular cystine does not take place in hepatocytes, where the reduction of cystine to cysteine occurs mainly in the outer cell membrane as a consequence of GSH efflux (11)