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Cell Mol Life Sci 74(21):38633881 Toader AM, Hoteiuc O, Bidian C, Oltean DD, Tabaran F, Grad O, Clichici S, Mitrea DR (2021) Neuronal apoptosis can be prevented by the combined therapy with melatonin and hypothermia in a neonatal rat model of hypoxic-ischemic encephalopathy

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Pre-phosphorylation of the serine residue resulted in a 2.68-fold increase in the Michaelis constant ( K m ) and a 6.25-fold increase in the maximum reaction rate ( V max ) when compared to the unprimed site