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48 h) inhibits FL5.12 prolymphocyte cells overexpressing Bcl-xL or Bcl-2 with EC 50 s of 60 nM and 20 nM, respectively

By employing ADAGPR, ADAMLP, and ADALASSO models, the research not only highlights the ability of these methods to capture intricate nonlinear relationships between solubility and key factorssuch as temperature (T), solvent composition, and mass fraction (w)but also underscores their relevance for optimizing solvent selection in drug development and other chemical processes