Now everyone is using them, seemingly, and one side effect in particular has stepped to the forefront of the conversation about GLP-1 use sudden and sometimes severe hair loss
Study selection Trial registries and databases (Medline, Embase, PsycINFO, CINAHL, Cochrane, Web of Science, and trial registries) were searched from inception until February 2025 for randomised controlled trials (RCTs), non-randomised trials, and observational studies that included WMM (8 weeks) with follow-up for 4 weeks after cessation of treatment in adults with overweight or obesity
Retrospective cohort studies show that these agents do not increase the risk of IBD flares or gastrointestinal-specific adverse events compared to the general population (9396)
In a related observation, PCs were used in a GDM mouse model with gut flora defects induced by a combination of broad-spectrum antibiotics and a high-fat, high-sugar diet