With everyone else gone, Knudsen was allotted the task to lead the way
Decrease sugar production in the liver
Empagliflozin had no clinically relevant effect on the pharmacokinetics of metformin, glimepiride, pioglitazone, sitagliptin, linagliptin, warfarin, digoxin, ramipril, simvastatin, hydrochlorothiazide, torsemide, and oral contraceptives when coadministered in healthy volunteers (see Figure 2)
These findings suggest that GLP-1 receptor agonists may be an option worth considering for type 2 diabetes patients at risk of RVO, potentially contributing to favorable long-term ocular outcomes and reducing the burden of visual impairment in this population, the researchers concluded in their paper.