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For example, participants with chronic kidney disease reported changes in IL-1, IL-6, and MMPs-9 and -12 (106), while we observed changes in IL-6, TARC/CCL17, IL-17A, I-TAC/CXCL11, Eotaxin-2/CCL24, Eotaxin/CCL11, and MIP-1a in our AD study participants (99)
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Pre-clinical studies have reported that these molecules quench reactive oxygen species (ROS), upregulate epidermal growth factor (EGF) signaling, and suppress matrix metalloproteinases (MMPs), thereby protecting fibroblasts and keratinocytes from ultraviolet (UV) stress and senescence
10.1038/s41598-019-48246-6 31
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