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Semaglutide is prescribed for lowering blood sugar levels for individuals with type 2 diabetes (T2D) and weight management for those who are overweight or have obesity with at least one weight-related comorbidity.[1-5] Individuals taking semaglutide may lose up to 15% of their body weight.[5] However, weight loss results may vary depending on your starting weight, comorbidities, other medications, and lifestyle choices.[1-5] Although the exact mechanism by which semaglutide causes weight loss is still under investigation, it has the potential to reduce appetite, thereby reducing caloric intake.[1-3] You may feel more tired than usual due to the reduced calorie intake while taking semaglutide

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Variants in your GLP1R gene and other metabolic pathway genes influence how strongly your body responds to semaglutide

S., Umapathysivam, M