glp-1 specialist indianapolis in Richard DiMarchi, pioneering IU peptide chemist behind many drugs, re-shapes obesity treatment: IU News How GLP-1 Injections Work for

Highlights: This review summarizes the strategies developed to date for the oral delivery of GLP-1 and its analogs in the treatment of obesity

The clinical implications are especially interesting because, although GLP-1 receptor agonists have been shown to benefit patients, they often do not produce sufficient metabolic improvement to achieve diabetes remission or to prevent major cardiovascular events among high-risk patients

The incidence risk ratio (IRR) was 0.82 for continuous GLP-1RA use, 0.88 for interrupted use, and 0.96 for discontinued use, relative to sulfonylurea use

The number to watch here is not just whether glucose drops, but whether it drops too far