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Early in vivo electrophysiological recordings showed that juxtacellular application of the active fragment of GLP-1, GLP-1 (736) amide induces an increase and then a decrease of firing activity in the hippocampal CA1 neurons

Gastroenterology 134 , 11371147 (2008)

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Food moves more slowly through the digestive tract, which extends fullness but it also means greasy, heavy meals hit very differently than they would otherwise