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It is an orphan drug designed and developed primarily by academic initiatives for the treatment of iron overload in thalassaemia, which is endemic in the Mediterranean, Middle East and South East Asia and is considered an orphan disease in the European Union and North America

The most common side effects of GLP-1 receptor agonists are gastrointestinal, including nausea, diarrhea, and vomiting, affecting 40-70% of patients

Notably concentrated in the skin, especially in the dermis and epidermis, vitamin C is essential for collagen synthesis, ensuring skin firmness, and for protecting against oxidative stress from UV radiation and pollutants

Referenced Citations Teichman, S