Phase 3 results will tell us more about long-term safety, cardiovascular outcomes, and how the drug performs in broader populations
Also, publication bias could change the effects of NAC on E2 levels and endometrial thickness
Contact your GP or diabetes specialist nurse if you experience: Severe, unrelenting nausea or vomiting lasting more than 24-48 hours, particularly if preventing adequate fluid or medication intake Persistent diarrhoea with signs of dehydration (dark urine, dizziness, reduced urination, dry mouth) Severe abdominal pain , especially if constant, worsening, or accompanied by fever Blood in vomit or stools , which requires urgent assessment Signs of dehydration require prompt intervention, particularly in vulnerable patients such as older adults or those with kidney disease
tingling (unbearable) in all limbs