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Patients taking certain medications (e.g., chloramphenicol may reduce the effectiveness of B12 therapy) or with risk factors for B12 deficiency (metformin use, proton pump inhibitors, nitrous oxide exposure, vegan diet) should discuss these with their healthcare provider

Subcutaneous injections deliver compounds into the fatty tissue beneath the skin, allowing for gradual absorption into the bloodstream

Vitamin B12 plays a critical role in energy production by converting fats and carbohydrates into usable energy, helping combat fatigue, especially on a calorie-restricted diet

RELATED The Bottom Line Your body needs vitamin B12 to create red blood cells and DNA, and to keep your brain and nervous system in top shape