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Clinical trials demonstrate significant efficacy, with semaglutide showing average weight loss of approximately 15% in the STEP trials and tirzepatide achieving up to 20% weight loss in the SURMOUNT trials, though individual responses vary considerably

PopracPJomovaKSimunkovaMKollarVRhodesCJValkoM.Targeting free radicals in oxidative stress-related human diseases

The dosage is incrementally increased over several weeks until a therapeutic or maintenance dose is reached