Germande O, Ducret T, Quignard JF, Deweirdt J, Freund-Michel V, Errera MH, Cardouat G, Vacher P, Muller B, Berger P, Guibert C, Baudrimont M, Baudrimont I (2022) NiONP-induced oxidative stress and mitochondrial impairment in an in vitro pulmonary vascular cell model mimicking endothelial dysfunction
Clinical response to statins: mechanism(s) of variable activity and adverse effects
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However, for the GLP-1-Am (2, -Glu-palm) analogue, the lipidation site close to N-terminal region of GLP-1 drastically decreased the peptide solubility, limiting it to pH 3, and resulted in the rapid aggregation into amyloid-like fibrils making this analogue unsuitable for further development