References consulted in writing this blog post: Jaime P Almandoz 1 , Thomas A Wadden 2 , Colleen Tewksbury 3 , Caroline M Apovian 4 , Angela Fitch 5 , Jamy D Ard 6 , Zhaoping Li 7 , Jesse Richards 8 , W Scott Butsch 9 , Irina Jouravskaya 10 , Kadie S Vanderman 11 , Lisa M Neff 10
Proposed perfusion/neurotransmitter mechanisms in a GLP-1 agonist sexual dysfunction case report may contribute to genital arousal pain or discomfort patterns in some patients, but generalisability is unknown
One study suggested that GLP-1RAs exert direct endothelial protective effects by activating the GLP-1R-dependent AMPK/Akt/eNOS pathway
Early clinical and preclinical data suggest benefits also in rheumatoid arthritis, osteoarthritis, osteoporosis, psoriasis, and hidradenitis suppurativa