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In the 2021 STEP-1 trial (1,961 adults with obesity or overweight), participants receiving semaglutide plus lifestyle intervention experienced a 14.9% mean weight loss after 68 weeks, while those on placebo lost only 2.4%

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In the 1980s, researchers identified a hormone in the human gut called GLP-1 that triggers the release of insulin, which controls blood sugar levels

Combating the disease early may help prevent its progression and reduce the risks of serious, lifelong complications7