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A phase 2 trial in adults with type 2 diabetes and a BMI of 27 kg/m 2 or more showed that combining the GLP-1 receptor agonist semaglutide with the long-acting analogue cagrilintide resulted in significantly greater weight loss (15.6%) compared with semaglutide alone (5.1%) and cagrilintide alone (8.1%) at 32 weeks