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2.2 Apoptosis assay The Annexin V/propidium iodide (PI) apoptosis assay was conducted with the Apoptosis Detection Kit (Lianke Bio, China)

Moving into Phase 3 MariTide is now advancing toward Phase 3 trials, which will evaluate: Long-term safety Real-world outcomes Comparisons with approved agents like Zepbound, Wegovy, and Ozempic Effects on obstructive sleep apnea, heart failure, kidney disease, and other cardiovascular risks Side Effects & Tolerability Like all GLP-1-based medications, MariTide can cause gastrointestinal side effects, especially during dose escalation

Seek immediate medical attention (call 999 or attend A&E) if you experience signs of a severe allergic reaction, including difficulty breathing, swelling of the face, lips, tongue, or throat, widespread urticaria, dizziness, or rapid heartbeat

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