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Method: Propensity score matching (to balance differences between groups such as age, obesity, sleep apnea)

Discussion Peptides have been widely used as ligands for targeted drug delivery and diagnostic imaging owing to their small size, ease of synthesis and functionalization, and high targeting affinity, thus combining the advantages of small molecules and biomacromolecules 41

The goal is to keep regain minimal enough that the reset period provides net benefit when medication is restarted with restored sensitivity

For example, semaglutide is available as two injectables: Wegovy for weight loss Ozempic for Type 2 diabetes It is also available as two oral tablets: Wegovy pill for weight loss Ozempic pill for Type 2 diabetes The dosing schedule also varies by indication, depending on how the medication was studied in clinical trials