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What is the role of GLP-1/GIP agonists in patients with overweight/obesity and/or type 2 diabetes

statistically significant improvement in motor symptoms Another trial with once-daily self-administered injections of liraglutide (1.2 or 1.8 mg, as tolerated) or placebo in 62 patients with PD reported improvements in MDS-UPDRS-2 (an activity of daily living scale), but not in MDS-UPDRS-3, in treated patients vs placebo

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This process, called desensitization or tachyphylaxis, is one reason why some people experience a "plateau" in tirzepatide effectiveness at a given dose