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Further, the thyroid gland of the patient with Hashimoto's disease does not organify normally(82) (Fig

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doi: 10.3389/fimmu.2023.1320362 201 PriceCLSharpPSNorthMERainbowSJKnightSC

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Activation of these membrane receptors triggers downstream changes in mitogen-activated protein kinase (MAPK) and phosphatidyl-inositol-3-kinase/AKT (PI3K/AKT) pathways, ultimately influencing gene transcription 61,62

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